During his first phase, Isaac makes the same crying sound as Mulligans.In the original Wrath of the Lamb DLC, the song was My Innermost Apocalypse.The term infanticide refers to the act of killing an infant or newborn. The music that plays during this boss fight is titled Infanticide.This supports the theory that Isaac has made peace with himself and realized what he must do, as seen through the multiple endings of the game. Isaac's expression as he changes phases during the fight goes from a somber, scared tone to him smiling in his third phase.Isaac, along with ?, teleport away upon defeat and do not "die".Isaac was added in the Wrath of the Lamb DLC for the original The Binding of Isaac.Glass Cannon no longer reduces health on use, so it can be used against Isaac much more effectively.Glass Cannon can also provide a high-damage initial shot, but doing this is extremely risky due to Glass Cannon's additional effect of reducing health to one half-heart. Methods of doing this include saving up a large amount of tears with Anti-Gravity, waiting for Kidney Stone to activate before shooting Isaac, or placing multiple bombs and detonating them all at once with Remote Detonator. This can be exploited to make the fight much easier by dealing large amounts of damage in the first hit. Isaac does not begin attacking until he has been damaged.Every time Isaac is defeated, the current savefile's image changes until The Polaroid is unlocked.RC Remote - Defeat Isaac, ?, Satan, and The Lamb as Tainted Jacob. Can perform all projectile patterns from the first phase.Shadows indicate ahead of time where the beams strike.He always performs this attack at the start of this phase and repeats this process every time he takes 200 damage. After teleporting back on-screen, he shoots the 10 lines of projectiles from the first phase. Teleports off-screen and summons Crack the Sky beams to cover the screen, starting from one of the top corners to the opposite bottom corner.During which he also performs the following attacks: Isaac grows a pair of angelic wings and is no longer stationary, moving towards where the player is predicted to go with short dashes. Summons 2 Crack the Sky beams at random locations.Shoots 8 projectiles in all directions.Shoots 4 projectiles in a cross pattern, which splits into four short-ranged projectiles after a short time, similar to Cricket's Body.Isaac alternates between two projectile patterns:.Isaac stands up but remains stationary and performs the following attack: Shoots 8 groups of long-range spinning projectiles along with 10 slightly curved lines of shorter-range projectiles in every direction.Shoots 8 groups of projectiles that curve back towards him.
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